Neanderthal DNA in Modern Humans

Non-African people carry remnants of the Neanderthal X chromosome, suggesting interbreeding with early human ancestors.

Written byJef Akst
| 1 min read

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FLICKR, ERICH FERDINAND

New evidence confirms suspicions that early modern humans, which left Africa some 300,000 to 750,000 years after Neanderthals, probably interbred with the physically stronger hominid species. The contact likely happened in the Middle East, the authors said, sometime after early modern humans left Africa 80,000 to 50,000 years ago.

Damian Labuda of the University of Montreal and the CHU Sainte-Justine Research Center and his colleagues analyzed a particular segment of the human X chromosome, one of the two sex chromosomes, known as dys44—an 8-kilobase intronic region that flanks the human dystrophin gene and has proved to be a useful marker for human evolutionary studies.Thanks to last year’s complete sequencing of the Neanderthal genome, the researchers could compare the genomes of more than 6,000 modern humans ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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