The copiousness of the Drosophila Down Syndrome cell adhesion molecule (Dscam), puzzles geneticists. Through alternative splicing, Dscam can produce 38,016 unique protein isoforms. Yet, no one has discerned a reason for such bounty. Andrew Chess and postdoc Guilherme Neves, at the Whitehead Institute for Biomedical Research, suggest that Dscam variants may serve as identity signatures to help individual neurons discern self from non-self.1In the study, microarray data revealed temporal and spati
The copiousness of the
In the study, microarray data revealed temporal and spatial expression differences for common alternatively spliced exons. Reverse-transcriptase PCR showed atht individual neurons even within the same cell populations produce a distinct array of proteins. A given R3/R4 photoreceptor cell, for example, produces a set of 15–50
The human homolog, DSCAM, does not ...
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Sino Biological’s trial program enables qualified customers to evaluate SuperNuclease Pro in their specific bioprocessing applications, facilitating faster technology assessment and informed decision-making during process development
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Resipher measures cellular respiration (OCR) continuously in standard 96-well plates inside your incubator, for days to weeks. No media swaps, dyes, or transfers. A live-cell functional readout for drug safety, metabolism, and mitochondrial health.
