New Leica camera for imaging live cells under near-native conditions

Leica Microsystems launches sCMOS microscope camera...


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Leica Microsystems launches the Leica DFC9000, a monochrome microscope camera with a highly sensitive third-generation sCMOS sensor. The camera enables researchers to image live cells under near-native conditions, allowing them to gain a better understanding of cellular processes and dynamics.

The Leica DFC9000 features an sCMOS sensor with high quantum efficiency over the entire spectrum of light, which provides a high signal-to-noise ratio to securely detect even faint signals. Compared to the second generation sensor, the maximum quantum efficiency increased by 14%, totaling up to 82% depending on wavelength as illustrated in the graphic below. In combination with a very low noise level, this results in a crisp fluorescence signal against a dark background – an effect very much desired in high-end fluorescence live cell imaging. The high sensitivity of the camera eliminates the need to monitor GFP-overexpressing specimens and protects cells from phototoxicity. The camera acquires full-frame images at ...

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