New NIH Procedures To Shield Clinicians From Grants Bias

As Mark Twain may--or, according to some sources, may not--have said about the weather, everybody has grumbled for years that National Institutes of Health peer-review study sections are stacked against clinical research, but nobody ever does anything about it. Now, that's changing, along with a lot of other standard operating procedures in NIH's peer-review system. NIH's Center for Scientific Review (CSR), which runs the panels that review about 70 percent of NIH grant applications, is about

| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

NIH's Center for Scientific Review (CSR), which runs the panels that review about 70 percent of NIH grant applications, is about to try several new devices to shield clinical-research proposals from unfair competition with laboratory experiments in peer-review panels dominated by basic scientists.

By the end of this year, CSR Director Ellie Ehrenfeld plans to create two new "special emphasis panels" for proposed patient-oriented experiments in oncology and cardiology, and to test a variety of approaches for clinical proposals that still don't seem to fit anywhere.

NEW DIRECTION: Under Director Ellie Ehrenfeld, NIH's Center for Scientific Review is trying to change the method and speed of grant approvals. Study-section bias has been a long-standing complaint of clinical researchers seeking NIH grants. Evaluating clinical-research proposals "does take special expertise," says Timothy Ley of Washington University in St. Louis, president of the American Society for Clinical Investigation (ASCI), and many CSR study ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Bruce Agnew

    This person does not yet have a bio.

Published In

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

fujirebio-square-logo

Fujirebio Receives Marketing Clearance for Lumipulse® G pTau 217/ β-Amyloid 1-42 Plasma Ratio In-Vitro Diagnostic Test

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours