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The C4880 dual-mode, cooled charge coupled device (CCD) camera is designed for use in measurements requiring low light and high dynamic range as well as in photometry and precision still-image acquisition. It has a sensitivity of 10 lx to 10-7 lx and a resolution of 1 million pixels (1,000 x 1,018 pixels). The C4880 offers both fast- and precision- scan modes. It has an analog-to-digital conversion rate of up to 10 MHz per pixel. Its digital output of up to 16 bits is compatible with most frame-grabber and display hardware on the market. The camera may also be controlled by computer through its RS-232C serial interface. Hamamatsu Corp., Bridgewater, NJ Circle No. 138 on Reader Service Card Version 2.0 of RFLPscan is a Windows-based software package for performing genetic analyses derived from DNA restriction fragment patterns, DNA fingerprints, protein typing patterns, and other identity-profiling gel images. It is able to analyze images obtained from film densitometers, flatbed scanners, CCD video cameras, storage phosphor devices, and radiometric detectors. The software offers comprehensive databasing capabilities that permit the comparison of lane profile data from gels as well as pairwise and simultaneous matching of individuals. Scanalytics, Billerica, MA Circle No. 139 on Reader Service Card ImageSpace 3.1 software was previously available only as a part of Molecular DynamicsU CLSM systems. The confocal package offers an integrated environment for rendering, processing, analysis, and display of confocal images, using an intuitive graphical user interface. Running on a Silicon Graphics workstation, ImageSpace software allows investigators to perform quantitative image analysis on three-dimensional data. Advanced analytical capabilities include automated object counting, seeding, and segmention; the program features tools for quantitative co-localization studies. The different 3-D analysis and 3-D visualization tools can be combined. Molecular Dynamics, Sunnyvale, CA Circle No. 140 on Reader Service Card The 215 Liquid Handler is an XYZ coordinate system robot that automates various manual liquid-handling procedures and sample- preparation protocols. It has the capability to pierce thick tube septa to reduce the risk of exposure to potentially hazardous or infectious samples. Non-piercing probes for open-tube sampling are also available. The system is fully programmable and performs with a positional accuracy of 1 0.5 mm in the X and Y axes. It features a built-in dilutor for autodilution tasks, a large selection of syringe sizes, 15 standard and thermostatic racks, and several tube options. Gilson Inc., Middleton, WI Circle No. 141 on Reader Service Card The Electro Cell Manipulator (ECM) 600 for electroporation of prokaryotic and eukaryotic cells features two voltage ranges (2.5 kV/500 V), an additive capacitor bank, and resistance timing, and makes possible instantaneous monitoring within a single unit. It is equipped with internal monitoring that measures true peak voltage and pulse length. The system includes a safety stand, cuvette rack, and a package of 50 sterile, disposable cuvettes in 1 mm, 2 mm, or 4 mm gap sizes. BTX Inc., San Diego, CA Circle No. 142 on Reader Service Card Offered For PCR Applications HotStart 100 storage and reaction tubes are 0.5 ml thin-wall polymerase chain reaction (PCR) tubes with a wax bead preadhered on the interior surface. The wax forms a uniform convective vapor barrier, which is said to reduce mispriming and primer oligomerization. The convective barrier also allows for separation of reaction components until the annealing temperature of the PCR reaction has been reached. The wax barrier seals the PCR product or prealiquotted master mixes for long-term storage in a lab freezer or standard refrigerator. Molecular Bio-Products Inc., San Diego, CA Circle No. 143 on Reader Service Card PROTEAN II xi cells perform a variety of separations, including SDS-PAGE, native, preparative, gradient, and high- resolution nucleic acid agarose electrophoresis. In addition, with the two-dimensional electrophoresis technique, they are able to separate in both the first and second dimension. The cells enable users to run one, two, or four slab gels, or up to 16 IEF tube gels simultaneously. They are available in 1 cm or 2 cm gel lengths with a selection of combs and spacers. Bio-Rad Laboratories, Hercules, CA Circle No. 144 on Reader Service Card The Chameleon kit is designed for single- and multiple-base substitution, insertion, and deletion mutations in virtually any double-stranded plasmid. Its site-elimination mutagenesis procedure introduces a new mutnS host strain, XLmutS, which is EndAQ. The endA mutation removes an endonuclease that degrades miniprep DNA. The kit can be used with almost any plasmid template containing a unique, nonessential restriction site and does not require CsCl-purified DNA. Stratagene, La Jolla, CA Circle No. 145 on Reader Service Card The SMART Colorimeter and SMART Reagents offer menu-driven operation for analysts measuring a variety of water-quality parameters. The SMART Colorimeter uses a tungsten lamp to deliver colorimetric analysis of absorbance readings from 1 to 2A and %T readings from 0 to 100 percent. In the laboratory or field, the alphabetical test selection plus 39 prepackaged reagents are designed to reduce analysis time and save on reagent time and preparation. Whatman LabSales Inc., Hillsboro, OR Circle No. 146 on Reader Service Card The LC-PVolume is a compact printer designed for evaluating the performance of volumetric equipment by means of gravimetric analysis. The single-balance system, based on guidelines from the National Committee for Clinical Laboratory Standards, automatically performs complex calculations and prints them in a user-defined report. Features of the system include storage of 60 programs, password protection, alphanumeric input, and a verification report for International Standards Organization and Good Laboratory Practices requirements. Mettler-Toledo Inc., Hightstown, NJ Circle #147 A new feature of MATLAB version 4.2c for Windows is the MATLAB Notebook, which integrates the softwareUs Technical Computing Environment with Microsoft Word 6.0. The Notebook Suite also provides an intuitive front-end for MATLAB through a dynamic link with Microsoft Word 6.0. This enables users to incorporate MATLAB graphics and commands directly into reports via a word-processing application interface; make changes in one portion of the document or any underlying data; and recalculate graphic and data results throughout the entire document. MathWorks Inc., Natick, MA Circle No. 148 on Reader Service Card

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October 1994

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