Worm Parents Pass on Behaviors Epigenetically to Offspring

Two research groups demonstrate that in Caenorhabditis elegans, behavioral traits can be passed down through the germline to future generations, even though they aren’t hard-wired.

Written byKatarina Zimmer
| 7 min read
c elegans transgenerational epigenetic inheritance behavior neuron genetics

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ABOVE: C. elegans
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Occasionally, as the nematode worm C. elegans meanders across rotten fruit on the prowl for bacteria to eat, it comes across ones it shouldn’t dine on. Some bacteria are lethal to the animals when ingested, and unfortunately, the worms can’t always distinguish them from the nutritious kind until it’s too late.

Nevertheless, this doesn’t stop them from teaching their young not to make the same mistake, researchers recently realized when watching the nematodes in the lab. Before the animals die from the pathogen, they often lay eggs. These offspring, researchers at Princeton University observed, consistently avoid that particular bacterial species. Evidently, pathogen avoidance—a behavioral habit the mothers learned towards the end of their lifetime—can be transmitted to the next generation, aiding their survival. But it’s not a hard-wired trait; instead, an epigenetic mechanism involving small RNAs appears to be responsible.

That’s the finding of a ...

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Meet the Author

  • katya katarina zimmer

    After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field of science and wanted to write about all of them. Following an internship with The Scientist in 2017, she’s been happily freelancing for a number of publications, covering everything from climate change to oncology. Katarina is a news correspondent for The Scientist and contributes occasional features to the magazine. Find her on Twitter @katarinazimmer and read her work on her website.

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