Odor Encoder

Ensembles of as few as 25 mushroom body neurons allow Drosophila to distinguish and react to specific odors.

Written byChris Palmer
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

VISUALIZING SMELL: Neurons in the mushroom bodies of Drosophila, shown in this composite image, help the flies discriminate among a large number of odors.COURTESY OF ROB CAMPBELL AND GLENN TURNER

The paper R.A.A. Campbell et al., “Imaging a population code for odor identity in the Drosophila mushroom body,” J Neurosci, 33:10568-81, 2013. The finding In the fruit fly (Drosophila melanogaster), pheromones and other highly salient odors have direct neural links to the brain from antennal olfactory receptor neurons. However, there are more smells that the flies must distinguish than there are odor-processing neurons, says Glenn Turner, a neuroscientist at Cold Spring Harbor Laboratory in New York. Imaging the brains of flies exposed to different smells, Turner and colleagues discovered that many odors are encoded by small, nonlocalized ensembles of neurons, allowing the insects to discriminate among vast numbers of closely related scents. The discrimination The researchers used two-photon calcium imaging to record neural activity in ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies