Papers to watch

K.M. Wassarman, R.M. Saecker, "Synthesis-mediated release of a small RNA inhibitor of RNA polymerase," Science, 314:1601-3, Dec. 3, 2006. "Besides confirming that the natural 6S RNA acts as a decoy by mimicry of the DNA promoter open complex, the authors show that inhibitory RNA can act as a transcriptional template, and that the inhibitory complex is destabilized by such transcription." Jim MaherMayo Clinic College of Medicine, United States

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

K.M. Wassarman, R.M. Saecker, "Synthesis-mediated release of a small RNA inhibitor of RNA polymerase," Science, 314:1601-3, Dec. 3, 2006.

"Besides confirming that the natural 6S RNA acts as a decoy by mimicry of the DNA promoter open complex, the authors show that inhibitory RNA can act as a transcriptional template, and that the inhibitory complex is destabilized by such transcription."

Jim Maher
Mayo Clinic College of Medicine, United States


R. Redon et al., "Global variation in copy number in the human genome," Nature, 444:444-54, Nov. 23, 2006.

"This study uses both [genotype data and array-based hybridizations] in the analysis of 270 individuals, the largest number yet examined. Remarkably, the authors find that 12% of the genome is contained in copy number variants."

Jonathan Flint
University of Oxford, United Kingdom


J. Ule, et al., "An RNA map predicting Nova-dependent splicing regulation," Nature, 444:580-6, Nov. 30, 2006 .

"Depending on the position of the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies