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Peptides, Made to Order

The use of synthetic peptides in life science research is growing as researchers in a wide variety of disciplines find applications for these reagents. Many of these peptides are easily produced by automated peptide synthesis, which enables the economic and relatively easy production of peptides in large quantities. As a result, many widely used, biologically active peptides are commercially available as pre-made catalog reagents.1 But when experimental approaches call for peptides that are not

Written byDeborah Fitzgerald
| 7 min read

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For academic researchers, many universities and institutes maintain their own core facilities for peptide synthesis. When such facilities are not available, or when they do not offer the exact services needed (e.g., a specific type of synthesis or desired quality control measure), an investigator can turn to one of the many external commercial sources. This profile details the various options that should be considered when choosing a custom peptide facility, including some general questions that should be addressed. Specific information about companies providing custom peptide synthesis services is presented in the accompanying table.

Researchers familiar with using custom services know that reputation, built from consistent results and word-of-mouth from other scientists, is perhaps the best way to estimate the quality of work done by a particular company. Researchers should also evaluate how closely each candidate matches the desired services, timeline, and budgetary constraints. There are many companies to choose from, ...

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