Recent Findings Lead to New Understanding of Dystonia

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is. Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation. Randolph J. Nudo Dystonias are movement disorders in which sustained muscle

Written byA. J. S. Rayl
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is.


Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation.

Randolph J. Nudo
Dystonias are movement disorders in which sustained muscle contractions cause involuntary twisting and repetitive movements or abnormal postures, classified by the body parts affected. Focal dystonias affect a single muscle or group of muscles; multifocal and segmental dystonias involve two or more groups of muscles; and generalized dystonia afflicts the whole body.

Focal dystonias are most prevalent. Among the most common are spasmodic torticollis, a condition where muscles in the neck cause the head to twist to one side; blepharospasm, where eye muscles forcibly close the eyelids; and ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies