Recent Findings Lead to New Understanding of Dystonia

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is. Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation. Randolph J. Nudo Dystonias are movement disorders in which sustained muscle

| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is.


Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation.

Randolph J. Nudo
Dystonias are movement disorders in which sustained muscle contractions cause involuntary twisting and repetitive movements or abnormal postures, classified by the body parts affected. Focal dystonias affect a single muscle or group of muscles; multifocal and segmental dystonias involve two or more groups of muscles; and generalized dystonia afflicts the whole body.

Focal dystonias are most prevalent. Among the most common are spasmodic torticollis, a condition where muscles in the neck cause the head to twist to one side; blepharospasm, where eye muscles forcibly close the eyelids; and ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • A. J. S. Rayl

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome