Recent Findings Lead to New Understanding of Dystonia

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is. Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation. Randolph J. Nudo Dystonias are movement disorders in which sustained muscle

Written byA. J. S. Rayl
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

Dystonia. It sounds like a dark, debilitating alien world--and for the estimated 300,000-plus people in North America alone who suffer the wrath of associated neurological disorders, it often is.


Effects of repetitive skilled finger movements on functional organization in a primate motor cortex, as measured by microelectrode stimulation. Training resulted in improved motor skill and expansion of digit representation.

Randolph J. Nudo
Dystonias are movement disorders in which sustained muscle contractions cause involuntary twisting and repetitive movements or abnormal postures, classified by the body parts affected. Focal dystonias affect a single muscle or group of muscles; multifocal and segmental dystonias involve two or more groups of muscles; and generalized dystonia afflicts the whole body.

Focal dystonias are most prevalent. Among the most common are spasmodic torticollis, a condition where muscles in the neck cause the head to twist to one side; blepharospasm, where eye muscles forcibly close the eyelids; and ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Published In

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research