Signal Transduction

Y.X. Huang, W.A. Paxton, S.M. Wolinsky, A.U. Neumann, L.Q. Zhang, T. He, S. Kang, D. Ceradini, Z.Q. Jin, K. Yazdanbakhsh, K. Kuntsman, D. Erickson, E. Dragon, N.R. Landau, J. Phair, D.D. Ho, R.A. Koup, "The role of a mutant CCR5 allele in HIV-1 transmission and disease progression," Nature Medicine, 2:1240-3, November 1996. (Cited in more than 150 papers since publication) Comments by David D. Ho, director of the Aaron Diamond AIDS Research Center at Rockefeller University, New York "We need


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Y.X. Huang, W.A. Paxton, S.M. Wolinsky, A.U. Neumann, L.Q. Zhang, T. He, S. Kang, D. Ceradini, Z.Q. Jin, K. Yazdanbakhsh, K. Kuntsman, D. Erickson, E. Dragon, N.R. Landau, J. Phair, D.D. Ho, R.A. Koup, "The role of a mutant CCR5 allele in HIV-1 transmission and disease progression," Nature Medicine, 2:1240-3, November 1996. (Cited in more than 150 papers since publication)

Comments by David D. Ho, director of the Aaron Diamond AIDS Research Center at Rockefeller University, New York

"We need inhibitors that will work against viruses that become resistant to the currently available drugs." It was an amazing anecdote. Researchers at the Aaron Diamond AIDS Research Center at Rockefeller University had identified subjects who repeatedly engaged in high-risk behavior that exposed them to HIV, but the subjects did not develop AIDS. "A couple of them had blood cells that were not infectable by HIV in a test tube," recalls David ...

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