Software for Modelling Freeze Drying Cycles

SP Scientific announces the introduction of the LyoModelling Calculator (LMC)

Written bySP Scientific
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

SP Scientific announces the introduction of the LyoModelling Calculator (LMC) - a powerful new software utility that enables those developing freeze drying cycles to calculate the time required for primary drying and the maximum product temperature based on user data input. This free software resource is available on the SP Scientific website**. Users obtain a starting point for primary drying duration and the maximum product temperature at the sublimation interface using pertinent information, such as shelf temperature and chamber pressure, from which an optimized freeze-drying cycle can be developed. The LMC is based on the steady-state heat and mass transfer model of primary drying developed by Dr. Michael Pikal with modifications by Dr. Robin Bogner and Royce Labriola at the University of Connecticut (USA). The LyoModelling Calculator was developed for aqueous product in vials in direct contact with the shelves in a lyophilizer. Primary drying phase is a very important ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

Parse Logo

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform