Where is a scientist to begin studying a newly cloned gene that has no apparent function or phenotype? A common approach for obtaining functional clues is to inactivate the gene either in vitro or in vivo and observe the outcome. Antisense technology provides a powerful technique to study the functional consequences of gene silencing without deleting the gene altogether.
In 1997 GENE TOOLS was founded as the only commercial source for research quantities of "Morpholino" oligos. The constituents of these chains differ from...
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