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In 1991, the Children's Hospital of Philadelphia (CHOP) and the Wistar Institute teamed up with Merck to develop a rotavirus vaccine to combat the illness that affects thousands of children every year. This partnership of an international pioneer in pediatric medicine, an independent biomedical research institute, and a giant pharmaceutical company produced the oral vaccine RotaTeq. Since its approval in February 2006, about 8 million doses have been distributed worldwide, immunizing an estimated three to five million children.
Rotavirus causes fever, vomiting, and diarrhea, and affects "most everyone" by age five, says Paul Offit, chief of Infectious Diseases at CHOP. "In the US, it causes about ...