Systems Biology Weathers the Storm

Systems Biology Weathers the Storm By Elie Dolgin ast December, in the face of one of the worst winter storms in decades, the Institute for Systems Biology declared a snow day. Most researchers stayed home, and a calm stillness transcended the Institute's three-story home overlooking Seattle's snow-crested Lake Union. Rows of stacked PCR machines sat unused, and the room full of mass spectrometry machines was silent—hardly the poster-image of

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By Elie Dolgin

ast December, in the face of one of the worst winter storms in decades, the Institute for Systems Biology declared a snow day. Most researchers stayed home, and a calm stillness transcended the Institute's three-story home overlooking Seattle's snow-crested Lake Union. Rows of stacked PCR machines sat unused, and the room full of mass spectrometry machines was silent—hardly the poster-image of systems biology.

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Yet in a small, darkened room, behind a flimsy, light-blocking curtain, action was lurking: Red LED's flashed, solenoid valves shuttered, and a rhythmic pulsing overpowered the slight hum of the machinery. Click, click, click. Click, click, click.

That morning, Lee Pang, a bioengineering postdoc in Nitin Baliga's lab, failed to dig his car out of the snow. But from the comfort of his own home, he was still operating ...

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