Mice with low vitamin D had exaggerated craving for opioids and felt the drugs’ effects more strongly—results supported in part by human medical records—suggesting that supplements should be explored as treatments for opioid use disorders.

A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.

The researchers say these findings challenge dogma in the field, which has given the liver all credit for metabolizing alcohol.

Join The Scientist on December 11 to discuss Yaa Gyasi’s sophomore novel, about a Stanford University neuroscience grad student navigating family issues, lab work, and her emerging identity.

In Chapter 14, author David Nutt describes the opioid crisis currently besetting the US.

Draconian drug laws harm citizens the world over. It’s high time to use sound science to change the landscape of prohibition.

Some rats showed a decrease in addictive tendencies when researchers activated the pathway, while the behavior of others became more addictive when the pathway was inhibited.

Bury your nose in tales of neurosyphilis, gender identity, the medical mysteries of sleep disorders, and more.

Preliminary findings from a clinical trial of heavy drinkers suggest that the drug can weaken certain memories tied to the reward of imbibing, although the mechanisms aren’t fully clear.

Kamran Khodakhah, a researcher at the Albert Einstein College of Medicine, explains the cerebellum's newly described role in addictive and social behaviors.

The Albert Einstein College of Medicine neuroscientist has revealed surprising functions of the brain region, such as its role in the brain’s rewards circuits and in addiction.

The author of a new book about emerging concepts in human genetics considers the question.

Oklahoma dropped its lawsuit against OxyContin-maker Purdue Pharma in exchange for a National Center for Addiction Studies and Treatment in Tulsa.

With a built-in supply of a powerful cocaine-chomping enzyme, the transplant might also curb addiction.

Lucemyra is the first non-opioid drug to be approved in the U.S. specifically for this purpose.

Take a break from the bench to puzzle and peruse.

An online survey finds that people report feeling most relaxed with a glass of red wine or beer, and most aggressive when drinking spirits.

The Dartmouth College professor uses optogenetics to probe the neurological routes of habitual behavior.

The primatologist had written to the agency that the trial, which involved observing the effects of nicotine addiction in squirrel monkeys, was “cruel and unnecessary.”