Brush-up Summaries

Fireflies glowing in a dark forest provide a captivating example of the luciferase-catalyzed bioluminescent reaction, which has been harnessed as a powerful research tool.
Luciferase: A Powerful Bioluminescent Research Tool
Priyom Bose, PhD | Jul 16, 2024 | 9 min read
Luciferase refers to a group of bioluminescence producing enzymes that enable researchers to study gene expression and regulation.
Synthetic Genomes: Rewriting the Blueprint of Life
Synthetic Genomes: Rewriting the Blueprint of Life
Priyom Bose, PhD | Jul 15, 2024 | 8 min read
Scientists construct synthetic genomes using computational and genetic engineering strategies to better understand complex biological systems.
A clear SDS-PAGE gel that contains multiple colored bands. 
Western Blot Protocol, Troubleshooting, and Applications
Rebecca Roberts, PhD | Jul 3, 2024 | 7 min read
Western blotting allows scientists to identify specific proteins in complex biological samples and determine relative abundance of a protein target.
A microscope and a model of a molecule, showcasing the power of atomic force microscopy for surface imaging at atomic resolution.
Atomic Force Microscopy to See the Invisible
Priyom Bose, PhD | Jun 24, 2024 | 8 min read
Atomic force microscopy (AFM) is a technique for visualizing a variety of samples, from single molecules to living cells, at ultrahigh resolution. 
Spherical viruses with spiked membrane proteins on their surfaces surround larger suspended cancer cells. 
Introduction to Oncolytic Virotherapy 
Amielle Moreno, PhD | Jun 13, 2024 | 8 min read
Oncolytic virotherapy selectively attacks tumors and triggers both immediate and long-lasting immune responses. 
In situ hybridization procedure being conducted in a laboratory.
Tips and Tricks for In Situ Hybridization
Priyom Bose, PhD | Jun 11, 2024 | 8 min read
In situ hybridization is a powerful molecular technique for detecting and localizing specific nucleic acids in cytological samples. 
A DNA strand and a barcode representing the DNA barcoding technique.
DNA Barcoding: Species Detection and High Throughput Assays
Priyom Bose, PhD | May 17, 2024 | 7 min read
DNA barcoding is a fast sequencing-based technique that scientists use to catalog all life on Earth or perform high throughput bioanalyses.
Industrial bioreactor with scientist in personal protective equipment
Introduction to Bioprocessing
Amielle Moreno, PhD | May 8, 2024 | 7 min read
Bioprocessing employs the transformative power of biochemistry to drive sustainable production and pharmaceutical development.
A scientist cultures organoids in a multi-well plate filled with red cell culture media
Understanding the 3D Cell Culture Revolution
Rebecca Roberts, PhD | Apr 17, 2024 | 6 min read
3D cell culture techniques closely mimic in vivo conditions, generating more accurate data for disease modeling and drug toxicity testing.
<strong >How Cloud Labs and Remote Research Shape Science&nbsp;</strong>
How Cloud Labs and Remote Research Shape Science 
Priyom Bose, PhD | Mar 18, 2024 | 6 min read
Remote research via cloud labs makes it possible for scientists to conduct complex experiments from a distance.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Blue circles arranged in five rows connected by wavy blue lines.
Artificial Neural Networks: Learning by Doing
Shelby Bradford, PhD | Mar 1, 2024 | 8 min read
Designed to mimic the brain itself, artificial neural networks use mathematical equations to identify and predict patterns in datasets and images.
Optimizing PCR: Proven Tips and Troubleshooting Tricks
Optimizing PCR: Proven Tips and Troubleshooting Tricks
Tanuka Biswas, PhD | Feb 23, 2024 | 10 min read
Scientists optimize PCR to ensure successful amplification and analysis.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
An automated sampler that is collecting a sample from a sewer line.
Tracking Community Health Through Wastewater Surveillance
Charlene Lancaster, PhD | Feb 1, 2024 | 8 min read
By monitoring disease biomarkers within wastewater, researchers gain insight into disease prevalence within communities.
An Overview of High Throughput Screening
An Overview of High Throughput Screening
Tanvir Khan, PhD | Jan 2, 2024 | 5 min read
High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples. 
<h1 >Precision Medicine: A New Era in Cancer Therapy</h1>
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD | Dec 15, 2023 | 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | Nov 14, 2023 | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
A blood test tube with the label &lsquo;cfDNA Screening&ndash;Test&rsquo;, held in a hand wearing blue gloves.
The Basics and Applications of Cell-Free DNA 
Rebecca Roberts, PhD | Nov 8, 2023 | 5 min read
Found circulating in peripheral blood, scientists use cell-free DNA (cfDNA) to assess genetic abnormalities, infections, cancer, transplant rejection, and cardiovascular disease.