Brush-up Summaries

A scientist cultures organoids in a multi-well plate filled with red cell culture media
Understanding the 3D Cell Culture Revolution
Rebecca Roberts, PhD | Apr 17, 2024 | 6 min read
3D cell culture techniques closely mimic in vivo conditions, generating more accurate data for disease modeling and drug toxicity testing.
<strong >How Cloud Labs and Remote Research Shape Science&nbsp;</strong>
How Cloud Labs and Remote Research Shape Science 
Priyom Bose, PhD | Mar 18, 2024 | 6 min read
Remote research via cloud labs makes it possible for scientists to conduct complex experiments from a distance.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Blue circles arranged in five rows connected by wavy blue lines.
Artificial Neural Networks: Learning by Doing
Shelby Bradford, PhD | Mar 1, 2024 | 8 min read
Designed to mimic the brain itself, artificial neural networks use mathematical equations to identify and predict patterns in datasets and images.
Optimizing PCR: Proven Tips and Troubleshooting Tricks
Optimizing PCR: Proven Tips and Troubleshooting Tricks
Tanuka Biswas, PhD | Feb 23, 2024 | 10 min read
Scientists optimize PCR to ensure successful amplification and analysis.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
An automated sampler that is collecting a sample from a sewer line.
Tracking Community Health Through Wastewater Surveillance
Charlene Lancaster, PhD | Feb 1, 2024 | 8 min read
By monitoring disease biomarkers within wastewater, researchers gain insight into disease prevalence within communities.
An Overview of High Throughput Screening
An Overview of High Throughput Screening
Tanvir Khan, PhD | Jan 2, 2024 | 5 min read
High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples. 
<h1 >Precision Medicine: A New Era in Cancer Therapy</h1>
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD | Dec 15, 2023 | 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | Nov 14, 2023 | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
A blood test tube with the label &lsquo;cfDNA Screening&ndash;Test&rsquo;, held in a hand wearing blue gloves.
The Basics and Applications of Cell-Free DNA 
Rebecca Roberts, PhD | Nov 8, 2023 | 5 min read
Found circulating in peripheral blood, scientists use cell-free DNA (cfDNA) to assess genetic abnormalities, infections, cancer, transplant rejection, and cardiovascular disease.
A scientist loads a 96-well plate containing qPCR reactions into a thermal cycler for DNA amplification and detection.
Insights into qPCR: Protocol, Detection Methods, and Analysis
Tanuka Biswas, PhD | Nov 8, 2023 | 6 min read
Learn about quantitative PCR (qPCR), including its fundamentals, common applications, modes of detection, and key quantification methods.
A semi-automated liquid handling robot with a multi-channel attachment for pipetting samples into an array format.
The Latest in Lab Automation
Deanna MacNeil, PhD | Oct 31, 2023 | 5 min read
As technologies advance, laboratory automation becomes reachable for researchers seeking high throughput approaches and reproducible results.
<em >Immunohistochemistry: Origins, Tips, and a Look to the Future</em>
Immunohistochemistry: Origins, Tips, and a Look to the Future
Steven Hrycaj, PhD | Oct 17, 2023 | 7 min read
An essential staining technique with a long history, immunohistochemistry (IHC) is being upgraded for modern research and clinical applications.
An Introduction to Metabolomics
An Introduction to Metabolomics
Rebecca Roberts, PhD | Oct 17, 2023 | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
A woman with diabetes checks her blood glucose levels using a wearable biosensor patch on her upper arm, transmitting the results to a smartphone.
Wearable Biosensors and Their Applications
Rebecca Roberts, PhD | Sep 11, 2023 | 5 min read
Allowing users to continually monitor biological signals over time, wearable biosensors pave the way toward personalized healthcare.
A person slouches while sitting at their laboratory bench, causing musculoskeletal strain, indicated by a yellow highlight on their spine.
Tips and Tricks for Improving Laboratory Ergonomics
Melissa Afterman, MS, CPE | Aug 16, 2023 | 4 min read
Proper ergonomics minimizes risk factors in the laboratory to optimize individuals’ performance and well-being.
The Ins and Outs of LC-MS
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | Jul 24, 2023 | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
An Introduction to Glycoproteins
An Introduction to Glycoproteins 
Rebecca Roberts, PhD | Jul 18, 2023 | 5 min read
Making up the majority of all eukaryotic proteins, glycoproteins have a wide range of important physiological roles, from cell-cell signaling to disease pathogenesis.