medicine

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.

A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.

An implantable device stimulates muscle contraction and prevents muscular atrophy in mice.

The experimental device, known as MAGENTA, forces muscles to contract, simulating natural movement. 

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

Researchers find that bacteria stimulate a headache-causing pain pathway to suppress the immune system and infect the brain. 

Researchers find that an increased heart rate can induce anxiety in mice, given the right context.

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

Public bathing, ubiquitous around the world and through the ages, plays an often-unappreciated role in public health.

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

Where and how human papillomavirus integrates itself into the human genome steers the infection’s clinical outcomes, finds a large, multifaceted study.

By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients.

Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.

The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice.