Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.

| 2 min read

What’s the Difference Between Gene Knockdown and Gene Knockout?

There are many techniques that allow scientists to silence a gene, but whether the effect is transient or permanent depends on the type of approach.

Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes.

| 5 min read

Stepping Into the Unknome

Image of the fly brain (grey) highlighting the population of neurons (pink) to which the gut-secreted peptide CCHa1 signals

| 3 min read

A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study

RNA interference

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RNA Interference Comes of Age

Diana Kwon | | 6 min read

RNAi Mechanisms in Neurodegenerative Disease Therapy

Available on Demand

Image of the Day: Horns and Wings

Emily Makowski | | 2 min read

First RNAi Therapy Approved by FDA

Kerry Grens | | 1 min read

RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder

Katarina Zimmer | | 2 min read

CRISPR System Targets RNA in Mammalian Cells

Anna Azvolinsky | | 4 min read

Vitamin C Blocks Leukemia Progression in Mice

Aggie Mika | | 4 min read

RNAi’s Future in Drug-Target Screening

Catherine Offord | | 5 min read

A Walk on the Wild Side

Mary Beth Aberlin | | 3 min read

RNA Interference Between Kingdoms

Kerry Grens | | 10+ min read

Oligonucleotide Therapeutics Near Approval

Catherine Offord | | 8 min read

Gut Bacteria for Insect RNAi

Ruth Williams | | 3 min read

Metazoans in the DNAi Club

Amanda B. Keener | | 2 min read

Ebola Drug Trial Terminated

Amanda B. Keener | | 2 min read

Improving Crops with RNAi

Narender NehraandNigel Taylor | | 2 min read

The Second Coming of RNAi

Eric Bender | | 10+ min read

Karmella Haynes: Turning the Dials

Kerry Grens | | 3 min read

Shushing RNA

Edyta Zielinska | | 2 min read

Circular RNA Surprise

Dan Cossins | | 2 min read

Going Boldly Forth

Karen Hopkin | | 9 min read

Page 1 of 2 - 24 Total Items

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Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

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What are the Risks and Benefits of a Cold Plunge?

Cold-water immersion enthusiasts tout its benefits for their health and wellbeing, but is it backed by scientific evidence?

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Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

The mitochondrial genome can help researchers map ancestry and better understand the inheritance of mitochondrial diseases.

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A Common Antidepressant Protects Organs from Damage During Sepsis

Fluoxetine, also known as Prozac, increased survival in a mouse model of sepsis, suggesting new therapeutic avenues for this life-threatening condition.

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Transform Omics Workflows with Scalable Cell Prep

Levitation-based cell enrichment streamlines workflows and enhances reproducibility.

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Accelerating Cancer Research Through Comprehensive Genomic Analysis

Learn how the latest technology helps researchers overcome cancer research challenges.

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May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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TaqMan Probe & Assays: Unveil What's Possible Together

Fuel your research with our high-quality TaqMan™ Assays and probes. Experience unmatched performance, reliability, and detailed support tailored to your scientific needs. Click to explore our comprehensive coverage options now!

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

In this webinar, Andre Mueller will introduce Aunty, the latest tool that scientists use for rapid, high-resolution protein stability testing.

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.

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Making Real-Time PCR More Straightforward

Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.

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Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.

Latest AI software simplifies image analysis and speeds up insights for scientists

The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.

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Agilent BioTek Cytation C10 Confocal Imaging Reader

From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.