Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.

| 2 min read

What’s the Difference Between Gene Knockdown and Gene Knockout?

There are many techniques that allow scientists to silence a gene, but whether the effect is transient or permanent depends on the type of approach.

Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes.

| 5 min read

Stepping Into the Unknome

Image of the fly brain (grey) highlighting the population of neurons (pink) to which the gut-secreted peptide CCHa1 signals

| 3 min read

A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study

RNA interference

oxalate cystal rnai rna interference alnylam sirna lumasiran Oxlumo Patisiran Onpattro givosiran Givlaari galnac inclisiran

RNA Interference Comes of Age

Diana Kwon | | 6 min read

RNAi Mechanisms in Neurodegenerative Disease Therapy

Available on Demand

Image of the Day: Horns and Wings

Emily Makowski | | 2 min read

First RNAi Therapy Approved by FDA

Kerry Grens | | 1 min read

RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder

Katarina Zimmer | | 2 min read

CRISPR System Targets RNA in Mammalian Cells

Anna Azvolinsky | | 4 min read

Vitamin C Blocks Leukemia Progression in Mice

Aggie Mika | | 4 min read

RNAi’s Future in Drug-Target Screening

Catherine Offord | | 5 min read

A Walk on the Wild Side

Mary Beth Aberlin | | 3 min read

RNA Interference Between Kingdoms

Kerry Grens | | 10+ min read

Oligonucleotide Therapeutics Near Approval

Catherine Offord | | 8 min read

Gut Bacteria for Insect RNAi

Ruth Williams | | 3 min read

Metazoans in the DNAi Club

Amanda B. Keener | | 2 min read

Ebola Drug Trial Terminated

Amanda B. Keener | | 2 min read

Improving Crops with RNAi

Narender NehraandNigel Taylor | | 2 min read

The Second Coming of RNAi

Eric Bender | | 10+ min read

Karmella Haynes: Turning the Dials

Kerry Grens | | 3 min read

Shushing RNA

Edyta Zielinska | | 2 min read

Circular RNA Surprise

Dan Cossins | | 2 min read

Going Boldly Forth

Karen Hopkin | | 9 min read

Page 1 of 2 - 24 Total Items

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Research Resources

Podcasts

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eBooks

Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

In this webinar, Ethan Shelkey and Aurita Menezes will highlight key aspects in the design of cell-based assays.

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From Water Bears to Grizzly Bears: Unusual Animal Models

Discover how alternative animal models provide new perspectives on physiological and biochemical processes.

Sex Differences in Neurological Research

Sex Differences in Neurological Research

Experts from the Women’s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.

New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Discover how scientists are designing the next groundbreaking vaccines against infectious diseases.

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Inventia Life Science Launches RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

Inventia Life Science, an innovator in 3D cell culture technologies, announces the launch of RASTRUM™ Allegro, a groundbreaking advancement in 3D cell culture technology designed to accelerate drug discovery and disease research with unprecedented scalability, reproducibility, and efficiency.

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Detecting Novel Viruses Using a Comprehensive Enrichment Panel

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