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Technology Transfer Pact Could Be A Model for Future Agreements

Also See: Breadth of Biodiversity After months of complaints, hundreds of scientists will finally be able to use a long-coveted recombinant technology without looking over their shoulders. On August 19, National Institutes of Health Director Harold Varmus announced an agreement with DuPont Pharmaceuticals that will enable NIH and NIH-supported researchers to use a DuPont-developed technology, called Cre-lox, without compromising the company's ability to receive the appropriate value for commer

Written byEugene Russo
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Also See: Breadth of Biodiversity

In a separate agreement with DuPont, the Jackson Laboratory, a nonprofit institution in Bar Harbor, Maine, and a designated national repository for genetically engineered mice, will be permitted to receive, breed, and distribute animals containing Cre-lox to both academic and commercial institutions. All parties contend that the agreements could serve as models for future agreements between academic and commercial research institutions.

"What we've worked [out] with the NIH is a role model for how commercial institutions can put important inventions for free into the academic domain while retaining commercial rights that are reasonable," claims David Block, vice president of product planning and acquisition at DuPont.

Cre-lox allows investigators to efficiently cut out or put in any size chunk of DNA into a designated sector of the genome. It's the first technology that's been proven to do so in post-mitotic cells such as liver cells. "We're ...

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