The Cheating Amoeba

The Cheating Amoeba Scanning electron micrograph of spore towers of the slime mold Dictyostelium discoideum. David Scharf / Photo Researchers, Inc What genes contribute to social interactions such as cheating or altruism? And what could cheating genes tell us about sociality, multicellularity, and cancer? A social soil amoeba could hold the answers. By Gad Shaulsky Related Articles Infographic: Dictyostelium Developmental Cycle Video: Social activ

Written byGad Shaulsky
| 12 min read

Register for free to listen to this article
Listen with Speechify
0:00
12:00
Share

What genes contribute to social interactions such as cheating or altruism? And what could cheating genes tell us about sociality, multicellularity, and cancer? A social soil amoeba could hold the answers.

By Gad Shaulsky

Infographic: Dictyostelium Developmental Cycle

Video: Social activity of D. discoideum

A Fluctuating Reality

Microbial Co-op in Evolution

Genetic control of social behavior

I was writing my thesis on the role of p53 in cancer in the early 1990s with a gas mask at my side. It was the first Gulf War, and the threat of Scud missiles that Iraq was launching at Israel made focusing on my thesis difficult. I had already decided to leave cancer research. I welcomed the distraction of reading about altruism, and about the strange little organism I had picked as a model of benevolent behavior: the social amoeba, Dictyostelium discoideum.

Those tumultuous days in Israel marked a major turning point in ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies