For this article, Steve Bunk interviewed Karl O. Stetter, director, Institute of Microbiology, University of Regensburg, Germany, and Jay M. Short, chief executive officer, Diversa Corp., San Diego. Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age.

G. Deckert, P.V. Warren, T. Gaasterland, W.G. Young, A.L. Lenox, D.E. Graham, R. Overbeek, M.A. Snead, M. Keller, M. Aujay, R. Huber, R.A. Feldman, J.M. Short, G.J. Olsen, R.V. Swanson, "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus," Nature, 392:353-8, March 26, 1998. (Cited in more than 255 papers since publication)

Increasingly, the tree of life is assuming the semblance of a bush. But even a bush has its deepest branches, and in presenting the first complete genome of a hyperthermophilic bacterium, this paper took important steps toward...

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