The First DNA Sequence Database

Credit: COURTESY OF GREG HAMM" /> Credit: COURTESY OF GREG HAMM In the middle of 1981, Greg Hamm was a 30-year-old software programmer newly hired by the European Molecular Biology Laboratory to head up its DNA data library-a database that did not yet exist. So he set about making one. "We had journals publishing sequence data in increasingly small point size type, which was useless," he says. "It was clear that one thing that was needed was a transmission format, a way to send the data f

Written byJeffrey M. Perkel
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

In the middle of 1981, Greg Hamm was a 30-year-old software programmer newly hired by the European Molecular Biology Laboratory to head up its DNA data library-a database that did not yet exist. So he set about making one. "We had journals publishing sequence data in increasingly small point size type, which was useless," he says. "It was clear that one thing that was needed was a transmission format, a way to send the data from one place to another."

Rather than limiting the system to the hardware at hand, Hamm decided to adopt an "archaic" file format that could be read by relatively simple and sophisticated systems both. "The decision I made was to reach backward in the history of computing to come up with a format," he says. "The idea was, if you had a very sophisticated environment, this format should be easy to parse. If you had ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

Cellecta logo
An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

Integra Logo

Products

brandtech logo

BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

Top Innovations 2026 Contest Image

Enter Our 2026 Top Innovations Contest

Biotium Logo

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS