Skip to main content

Tobacco Plants Make HIV Antibody

For the first time, a plant-produced antibody gets the green light for clinical trials in the United Kingdom.

Written byCristina Luiggi
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00

FLICKR, UNIVERSAL POPS

Last month, a monoclonal antibody produced in the leaves of tobacco plants entered phase I clinical trials in the United Kingdom. The antibody, known as P2G12, recognizes an HIV surface protein and is expected to help stop the transmission of the virus, although it has never been tested in humans. The phase I trial, underway at the University of Surrey, will test the safety of vaginally applying the antibody to 11 healthy women.

This is the first plant-produced antibody to be cleared for clinical trials by the Medicines and Healthcare Products Agency (the UK equivalent of the US Food and Drug Administration). Producing the antibody using tobacco plants grown in a greenhouse in Germany is 10 to 100 times cheaper than using conventional methods employing ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

Danaher Logo

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays