Watching Wolfson

Watching Wolfson In 12 years, the UK institute has produced 600 papers, 6 spin-offs, and 31 patents. Does this mean its unique approach is working? By Stephen Pincock Related Articles 1 and new details on how a nitric oxide-cGMP-dependent pathway controls mitochondrial biogenesis and the body's energy balance.2,3 The standout feature of the institute is the way it has managed to achieve genuine interaction among researchers of different disciplines,

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By Stephen Pincock

1 and new details on how a nitric oxide-cGMP-dependent pathway controls mitochondrial biogenesis and the body's energy balance.2,3

The standout feature of the institute is the way it has managed to achieve genuine interaction among researchers of different disciplines, says WIBR collaborator Mary Collins, a researcher based at University College London (UCL). "The interdisciplinary thing is fantastic," she says. "Getting medicinal chemists alongside biologists is quite hard to do in academia."

Jim Smith, director of the Gurdon Institute at the University of Cambridge, agrees. "It's a terrific idea to bring together groups in fields that normally don't speak to one another," he says. "That sort of interaction is where you get new ideas."

The WIBR is the brainchild of Salvador Moncada, a Honduras-born investigator and 40-year UK resident, who achieved notoriety when he discovered the cardiovascular effects of nitric oxide.4 In the 1990s, Moncada had a vision: ...

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