Scientists have employed mouse models in immunological studies for over a century; however, these models, much like other systems, are unable to perfectly recapitulate the human immune system. To address this problem, researchers have developed various methods to humanize their mouse models and make them more translatable for drug studies.
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- How to generate humanized mouse models through human cell and tissue engraftment
- The history of immunodeficient mice and their role in immunological research
