Ancient Europeans Were Lactose Intolerant

Five-thousand years after agricultural practices spread across Neolithic Europe, human populations remained unable to digest sugars from the milk of mammals.

Written byBob Grant
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Bauersfrau mit drei Kälbchen, by Henry Hetherington EmmersonWIKIMEDIA, NAGEL AUKTIONENWell after agriculture blossomed across Europe, its practitioners remained lactose intolerant, even as the consumption of milk and dairy products from domesticated animals became commonplace, according to new research. Studying ancient DNA extracted from skulls that dated from 5,700 BC to 800 BC, scientists from University College Dublin and their colleagues determined that ancient Europeans carried the genes for lactose intolerance. The team published its findings, which illustrate the genetic changes that lag behind cultural shifts, today (October 21) in Nature Communications.

“The genomes do seem to shift as new technologies come about,” coauthor and Trinity College Dublin research Daniel Bradley told the Washington Post. “You can’t look at this and think that farming and metallurgy are technologies that come into the culture by osmosis. They come with people. Genomes and technology migrate together.”

In addition to the insights they garnered regarding the genetic makeup of ancient Europeans, the study’s authors also contributed to the methodological advancement of extracting useable ancient DNA by learning that the petrous bones of the skull are ideal for such analyses. “The high percentage DNA yield from the petrous bones exceeded those from other bones by up to 183-fold,” study coauthor Ron Pinhasi from the UCD Earth Institute and UCD School of ...

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  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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