Ancient Genomes Reveal Secrets

New Neanderthal and Denisovan genomes point to the existence of an unidentified early human.

Written byAbby Olena, PhD
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Denisova Cave in SiberiaEUREKALERT, MPI FOR EVOLUTIONARY ANTHROPOLOGYNew, high-quality genome sequences from Neanderthal and Denisovan remains suggest that these two groups interbred frequently with other ancient human ancestors and anatomically modern humans. The sequences also revealed evidence of interbreeding with another unidentified human ancestor. The work, led by David Reich of Harvard Medical School in Boston, Massachusetts, was presented at a meeting of The Royal Society focused on ancient DNA this week (November 18).

“What it begins to suggest is that we’re looking at a ‘Lord of the Rings’-type world—that there were many hominid populations,” Mark Thomas from University College London, who did not participate in the work, told Nature News.

Even though Denisovan and Neanderthal genomes had been sequenced before, Reich explained at the meeting that the sequences were of low quality, according to Nature. Using bones recovered from a cave in Siberia, Reich and his colleagues generated much-improved sequences. The superior genomes showed that the Denisovans produced offspring with another group of unknown ancient hominins that probably lived in Asia more than 30,000 years ago, Reich told Nature.

“There’s a very strong signal, difficult to question,” Johannes Krause of the University of Tubingen, who was not involved ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies