And Then There was Y

The Y chromosome gets no respect.

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Courtesy of Flashback Imaging

The Y chromosome gets no respect. Regarded as a genetic junkyard with little to offer but sex, genomes have commonly rolled off the presses without a nod to Y. Then there's the matter of decay. Without a recombination partner, genetic insults whittle away the already diminutive Y, suggesting the chromosome's, and by extension man's, eventual extinction.

But this issue's Hot Papers refute the entrenched view of the Y chromosome. One showcases its sequence,1 and the other sizes up the male chromosome across humans and other primates.2 The emerging picture turns out to be not so bleak for the fate of man. The studies reveal a crafty recombination method, ensuring Y's survival for generations. Recent work making comparisons with the completed chimpanzee genome has increased the clarity of the Y portrait, but also left a few new questions.3

X and Y are believed to have arisen from ...

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