D. Muller, G. Unbricht, B. Weber, A. Pfaltz, "C2-Symmetric 4,41,5,51-tetrahydro-21-methylenebis[oxazoles] as chiral ligands for enantioselective catalysis," Helvetica Chimica Acta, 74 (1), 232-38, 1991. (University of Basel, Switzerland)
Two recent papers illustrate how remote binding sites in substrates can coordinate to transition metal catalysts and alter reactions. In the first, a remote alkene controls the direction of a palladium hydride elimination. In the second, a remote alkyne delivers a palladium catalyst to a hindered allylic acetate that was otherwise completely unreactive.
B.M. Trost, M. Lautens, C. Chan, D.J. Jebaratnam, T. Mueller, "Annulation via alkylation-alder ene cyclizations. Pd-catalyzed cycloisomerization of 1,6-enynes," Journal of the American Chemical Society (JACS), 113, 636-44, 16 January 1991. (Stanford University, Calif.; University of Wisconsin, Madison) B.M. Trost, A.S. Tasker, G. Rüther, A. Brandes, "Activation in transition-metal catalysis by catalyst relay. A synthetic approach to (-)-dendrobine," JACS, 113, 670-2, 16 January 1991. (Stanford University, Calif.)
Selective conditions to ...
