Bovine pulmonary artery endothelial cells stained with Molecular Probes' MitoTracker Red and SYTOX green nucleic acid stain Tools for Mitochondrial Research Table Fifty years ago, mitochondrial research was at the forefront of biology. The elucidation of the citric acid (Krebs) cycle, the mechanisms of oxidative phosphorylation, and the electron transport system (ETS) were arguably some of the most important breakthroughs in cellular biology. Soon interest waned, and the focus of research moved

Thermal Cyclers So much has changed in the last half-decade in the world of gene amplification. New breakthroughs and protocols have exceeded scientists' wildest expectations for applications of this essential technology. Is there a single life science lab in the country without a thermal cycler? From the high-end, ultrafast light-based cyclers to the tiny personal cyclers, there is a cycler to fit every need. Way back in the early years of PCR, "doing an amplification" meant simply that--

The personal computer continues to evolve, further relieving scientists from tedious and mundane tasks. The extra time made available by computer assistance allows increased productivity and may pay off with faster and more profound discoveries. Linking individual computers through a network or the World Wide Web allows access to remote databases and instantaneous reporting of results, increasing efficiency. Computers have come a long way from the first handheld calculators that could perform

Date: September 27, 1999Laboratory Database Systems The collective mantra of the scientific community seems to be "Data! Data! Data!" New high-throughput devices generate mountains of data in a matter of minutes. Without some way to manage this information, a researcher can be quickly mired in "information overload." Laboratory database software systems provide a convenient way to centralize, archive, and secure data generated by many sources. These systems can reduce clutter, speed communicati

Date: July 5, 1999Products for High-Volume Tissue Culture The Automation Partnership's CELLMATETM Automated Cell Culture Processing System Mammalian cell culture has finally come into its own as a way to produce cells, proteins, or sub-cellular components in large scale. Recent advances in cell culture systems are allowing scientists to better circumvent problems associated with bacterial systems such as incomplete protein expression, toxin contamination, and incompatibility. Today's wide arra