Date: July 5, 1999Products for High-Volume Tissue Culture

The Automation Partnership's CELLMATETM Automated Cell Culture Processing System
Mammalian cell culture has finally come into its own as a way to produce cells, proteins, or sub-cellular components in large scale. Recent advances in cell culture systems are allowing scientists to better circumvent problems associated with bacterial systems such as incomplete protein expression, toxin contamination, and incompatibility. Today's wide array of flasks, bottles, reactors, and controllers allow even the smallest lab to scale up quickly and economically. The system of choice depends on a number of factors: lab resources, type and quantity of the desired product, the frequency and duration of the project, and the cell type used.

This article focuses on tools to scale up cell culture for the occasional research study and even full-scale industrial production. The table summarizes the various culture systems and manufacturers. Tools for cell...

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