FEATURELab Design Redesign and the Bottom LineBY ISHANI GANGULI PHOTOS: ISHANI GANGULI Above, a soon-to-be production room, where production manager Randy Caise "went through 40 rolls of tape" to fit as many centrifuges, laminar flow hoods, and incubators as possible. Percifield calls it an efficient use of space.Left, Percifield draws out a production schematic for Lentigen. According to him, the company

Scientists find first 5' promoter element in dengue genome, perhaps explaining why virus loops before being copied

Female scientists are authoring more original research papers, but publishing rates still don't match women's enrollment in medicine

'Father of gene therapy' faces years in jail for molesting a young girl; University bars him from campus, strips him of tenure and faculty position

FEATUREComplement   Margarita Soto: A life with PNHBY ISHANI GANGULIARTICLE EXTRASRelated Article:A Complement PathwayA Complement RenaissanceInfographics: Interrupting ComplementPaths to MarketMargarita Soto had her first blood transfusion to treat her anemia at the age of 16, when she was pregnant with her second child in Puerto Rico. She began to notice her urine was dark soon after, an

FEATUREComplement Margarita Soto: A life with PNHBY ISHANI GANGULIMargarita Soto had her first blood transfusion to treat her anemia at the age of 16, when she was pregnant with her second child in Puerto Rico. She began to notice her urine was dark soon after, and by the age of 18, in the worst of her hemolytic episodes, pain and exhaustion from her anemia kept her from walking up stairs, let alone playing volleybal

At Harvard, biology is an endangered species. Next fall's wide-eyed freshmen will have to head down the street to Massachusetts Institute of Technology if they want to concentrate (Harvard-speak for major) in the subject, because it will no longer be offered in Harvard Square. This change was puzzling to my editor, who concentrated in biology at Harvard, and to me, a 2005 graduate with a degree in biochemistry. So I consulted Robert Lue, my former advisor and cochair

Katherine Fitzgerald: Waiting, but not in vain

FEATUREComplement How one group of researchers brought a scientific idea to the clinic for a rare diseaseBY ISHANI GANGULI© THOM GRAVESScott Rollins was starting his graduate thesis at Oklahoma Medical Research Foundation in the late 1980s when he first heard about paroxysmal nocturnal hemoglobinuria (PNH). He learned that in PNH, red blood cells are vulnerable to attack by the complement system's terminal membrane-attack complex. Pat

Adults become more sensitive to pain after watching other mice in pain, the first sign of empathy in non-primate mammals

Last evening, during Edward O. Wilson?s Baptist sermon-like address to an auditorium of 600 diverse faces at the American Museum of Natural History, the environment and its advocates got a bit of a pep talk. With the eminent naturalist?s signature articulacy, humor, and frankness (take "Soccer moms are the greatest enemy of natural history," or "It might have been a big mistake to give economics a Nobel Prize"), he took on the case for studying and preserving biodiversity. N

Credit: COURTESY OF THE J. DAVID GLADSTONE INSTITUTES" /> Credit: COURTESY OF THE J. DAVID GLADSTONE INSTITUTESLast spring, Sue Saunders was writing a grant proposal for the elementary school where she runs an after-school literacy program, when a conversation with her daughter Laura, a postdoc studying cancer biology at the J. David Gladstone Institutes, gave her an idea.Every month, Laura and a few fellow postdocs had been visiting Junipero Serra Elementary School in Bernal