Too Much to Untangle By Michael Szpir Genes and the environment both contribute to autoimmune diseases, and future advances could come from studying these factors in combination. ARTICLE EXTRAS Ultraviolet Light and Lupus Drugs, Diet, and Lupus Smoking and Rheumatoid Arthritis Iodine and Autoimmune Thyroid Disease Ultraviolet Light and Dermatomyositis Why anyone develops an autoimmune disease is

Ultraviolet Light and Lupus ARTICLE EXTRAS Too Much to Untangle Drugs, Diet, and Lupus Smoking and Rheumatoid Arthritis Iodine and Autoimmune Thyroid Disease Ultraviolet Light and Dermatomyositis Sunlight can worsen rashes and even trigger a flare-up of the disease in some people with lupus. It is well known that sun-sensitive lupus patients carry certain variants of the HLA genes, but those are

Drugs, Diet, and Lupus ARTICLE EXTRAS Too Much to Untangle Ultraviolet Light and Lupus Smoking and Rheumatoid Arthritis Iodine and Autoimmune Thyroid Disease Ultraviolet Light and Dermatomyositis One of the best examples of a gene-environment interaction in autoimmunity involves instances in which certain drugs produce a lupus-like syndrome in genetically susceptible individuals. It turns out

Smoking and Rheumatoid Arthritis ARTICLE EXTRAS Too Much to Untangle Ultraviolet Light and Lupus Drugs, Diet, and Lupus Iodine and Autoimmune Thyroid Disease Ultraviolet Light and Dermatomyositis Recently, Lars Klareskog at the Karolinska Institute and his colleagues described a strong gene-environment interaction in a subset of people with rheumatoid arthritis (RA) (L. Klareskog et al., "Genes,

Iodine and Autoimmune Thyroid Diseases ARTICLE EXTRAS Too Much to Untangle Ultraviolet Light and Lupus Drugs, Diet, and Lupus Smoking and Rheumatoid Arthritis Ultraviolet Light and Dermatomyositis A number of clinical and epidemiological studies suggest that the incidence of autoimmune thyroid diseases (AITDs), such as Hashimoto thyroiditis and Graves disease, goes up as dietary iodine increas

Ultraviolet Light and Dermatomyositis ARTICLE EXTRAS Too Much to Untangle Ultraviolet Light and Lupus Drugs, Diet, and Lupus Smoking and Rheumatoid Arthritis Iodine and Autoimmune Thyroid Disease Dermatomyositis is a connective-tissue disease that is characterized by inflammation of the skin and the muscles. Exposure to sunlight, either occupationally or recreationally, is anecdotally associa

Take some cells from a patient, grow them in a laboratory for a few weeks, and then inject them back into the same patient.

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