An ACE in the Hole for Cellular Therapies

Take some cells from a patient, grow them in a laboratory for a few weeks, and then inject them back into the same patient.

Written byMichael Szpir
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Courtesy of Isolagen

Take some cells from a patient, grow them in a laboratory for a few weeks, and then inject them back into the same patient. That's the basis for autologous cellular therapy, a rapidly developing field that promises to revolutionize the treatment of conditions from cancer to crow's feet.

Growing the cells can be quite labor-intensive, however, because they must be transferred into increasingly larger flasks as they propagate. An Exton, Pa.-based company called Isolagen http://www.isolagen.com, which specializes in autologous cellular therapies for tissue regeneration, hopes to improve this process.

About three years ago, scientists and engineers at Isolagen began working on an automated, "closed-loop" system that reduces the need for human intervention. The result is the automated cellular expansion (ACE) system, unveiled at the UBS 2005 Global Pharmaceuticals Conference in May.

"When you grow cells in a laboratory with the traditional methods, you might have 200 to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

cytiva logo
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo
Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

cytiva logo

Products

sartorius-logo

Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

parse_logo

Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

shiftbioscience

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

brandtechscientific-logo

BRANDTECH Scientific Launches New Website for VACUU·LAN® Lab Vacuum Systems