Indianapolis is the center for research and development for Eli Lilly and Co. Scientists at large pharmaceutical companies have access to colleagues in diverse areas. As a result, an individual may stumble across an opportunity that leads to a diversion from a logical career progression. Hedberg adds, "It is important to know that you have the responsibility for your own career management. If you are interested in pursuing these opportunities they are there for you to sample, but you have

Brain development is an awesome feat. Over a trillion neurons make connections with thousands of target cells to create coherent circuits for vision, language, movement, and memory. Most neurons migrate from their birthplace to their permanent home in the developing brain. Once they find a home, some cells send growth cones to different parts of the brain, creating networks with their axons. Corey Goodman, professor of molecular biology at the University of California, Berkeley, elaborates, "Th

Steps in positional cloning. Positioning of disease loci to chromosomal regions requires multidisciplinary collaborations. "You have a clinician out in Israel gathering patients, a medical geneticist doing genetic mapping, my lab doing physical mapping, and Washington University sequencing. All these things come together and, boom, in record time you have this gene," says Green. Green goes on to point out that this is a classic example of finding a gene from sequences the Human Genome P

Women with an increased risk of breast cancer don't have to helplessly wait and wonder if they'll find that dreaded tumor. They have the choice to pursue a preventive course of action. The first national breast cancer prevention trial sponsored by the National Cancer Institute (NCI) proved the drug tamoxifen cut the risk of breast cancer in half for women at high risk.1 Following this finding the Food and Drug Administration (FDA) approved the use of tamoxifen as a preventive measure in October

"Drink milk," advertisements demand. Fight osteoporosis before bone loss occurs. They make a good point, considering that nothing on the market will restore a significant amount of lost bone mass. Current therapies can only stop or help slow down the process. However, scientists at Chiroscience Research and Development in Bothell, Wash., hope to actually treat osteoporosis. They have identified a novel gene coding for a protein that may be involved in bone-density control. This "bone mass gene

Biochemist John Carson uses The Virtual Cell to compare experimental and simulation results. Biologists are generating a vast amount of data on the molecular events that occur in the cell. Since a computer might the best tool for researchers to integrate all the information and sort out the complexities of a typical biological process, the next logical step would be to develop appropriate software for the job. A team at the University of Connecticut (UConn) Health Center in Farmington is attemp