Automated Staining

Possibly the most difficult aspect of manual histopathological staining is maintaining consistency. BioGenex of San Ramon, Calif., has overcome this problem with the introduction of the i6000 Automated Tissue and Cell Staining System, the successor to the OptiMax Plus.1 Philipp Novales-Li, director of scientific affairs at BioGenex, states that the i6000 "allows for industrial-scale and high-throughput walkaway automation, while bringing about standardized, accurate, and reliable results." At 30

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"Initial staining runs have given excellent quality, with a very rapid learning curve for the technologists," says Clive Taylor, chair of the Department of Pathology at the University of Southern California School of Medicine. Massimo Loda, director of the ISH facility at the Dana-Farber Cancer Institute in Boston, has used the i6000 to perform IHC analyses. Loda was impressed by the quality of staining and the reproducibility of results generated by the system.

The i6000 system operates in Windows NT and can display slide and reagent maps depicting the process under way. The system has a capacity for 60 slides and 60 reagents and allows continuous access by the pathologist to remove stained slides or add new ones during the run. The reagents and slides are bar-coded to optimize workflow efficiency. The system can perform reagent inventory to identify insufficient or expired reagents, and an automated test inventory indicates the ...

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