Awakening Oligodendrocyte Precursors: Recent Advances in Remyelination

The Scientist is bringing together a panel of experts to share their research into remyelination strategies, across diverse diseases, and to discuss the current body of evidence for oligodendrocyte precursor reprogramming.

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Myelin provides important structural, electrical, and trophic support in the central nervous system (CNS), and several diseases interfere with normal myelination, causing axonal demyelination or hypomyelination. Defects in myelination impair normal action potential propagation and dampen axonal conductivity. Remediating the conductivity between neurons in the pathological setting has proven difficult, as oligodendrocyte precursor cell (OPC) reprogramming has not, to date, been feasible on a large scale. To explore whether or not remyelination is an achievable therapeutic target in diseases such as multiple sclerosis and schizophrenia, The Scientist is bringing together a panel of experts to discuss the current body of evidence. Attendees will have the opportunity to interact with the experts, ask questions, and seek advice on topics related to their research.

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