ANDRZEJ KRAUZE
A few years ago, tumor immunologist Elizabeth Repasky realized that she had heard from too many oncologists, colleagues, and friends that cancer patients regularly reported feeling cold and unable to regulate their internal thermometers. At her lab at the Roswell Park Cancer Institute in Buffalo, New York, she decided to build on her experience studying thermal physiology and immunology to see exactly what might be going on with regard to temperature and cancer. “I’ve always gone around telling people it’s really important to be warm,” she says. “Being warm is a really important part of dealing with diseases like cancer.”
Laboratory mice are routinely held at temperatures well below what’s called their “thermoneutral zone,” or the temperature range in which their metabolism functions most efficiently, ...