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Microscopy image of hepatocytes stained in pink with purple nuclei.
Liver Proteins Keep T Cells Out of Tumors
A new study finds an unexpected role for hepatocytes in anticancer immunity.
Liver Proteins Keep T Cells Out of Tumors
Liver Proteins Keep T Cells Out of Tumors

A new study finds an unexpected role for hepatocytes in anticancer immunity.

A new study finds an unexpected role for hepatocytes in anticancer immunity.

tumor immunology

Four circular maps of color-coded immune cell types corresponding to the four tumor microenvironment archetypes.
A Bird’s Eye View of the Tumor Microenvironment
Kamal Nahas, PhD | Jun 3, 2024 | 3 min read
Immune cells form different communities throughout a tumor, potentially disrupting how cancers respond to treatments.
Bispecific Antibodies Treat Cancer in Mouse Models
Abby Olena, PhD | Mar 5, 2021 | 4 min read
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Daniel E. Speiser and Werner Held | Jul 13, 2020 | 9 min read
Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.
Transplant Method Avoids Rejection of Donor Leg for Months in Rats
Abby Olena, PhD | Mar 13, 2020 | 4 min read
A proof-of-concept study uses a strategy similar to the way tumors evade immune detection. The new limbs survive for more than 200 days.
Brrrr-ying the Results
Bob Grant | Jul 1, 2015 | 5 min read
Holding laboratory mice at temperatures lower than those the animals prefer could be altering their physiology and skewing experimental results.
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