Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.
Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Harnessing Stem Cell–Like T Cells to Better Fight Cancer

Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.

Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.

cancer immunology
Miracle Elixirs
Miracle Elixirs
Bob Grant | Mar 31, 2019
A long way into the quest to vanquish cancer, our ears strain to hear the words, “Cancer is cured”—a yearning that can cloud our judgment.
The Next Frontier of CAR T-Cell Therapy: Solid Tumors
The Next Frontier of CAR T-Cell Therapy: Solid Tumors
Kerry Grens | Mar 31, 2019
The technology has wowed the field by all but obliterating some patients’ blood cancers, but solid malignancies present new challenges.
Making CAR T-Cell Therapy Safer
Making CAR T-Cell Therapy Safer
Catherine Offord | Mar 31, 2017
Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Neoantigens Enable Personalized Cancer Immunotherapy
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
AACR Q&A: Elaine Mardis
AACR Q&A: Elaine Mardis
The Scientist Staff | Apr 18, 2016
The genomics pioneer shares the sessions she most looks forward to at this year’s American Association for Cancer Research annual meeting.
Napster Cofounder Launches Cancer Initiative
Napster Cofounder Launches Cancer Initiative
Bob Grant | Apr 13, 2016
Billionaire Silicon Valley entrepreneur Sean Parker donates $250 million to unite the cancer research community around the common goal of developing new immunotherapies.
Microbes Meet Cancer
Microbes Meet Cancer
Kate Yandell | Mar 31, 2016
Understanding cancer’s relationship with the human microbiome could transform immune-modulating therapies.
Immune Influence
Immune Influence
Kate Yandell | Mar 31, 2016
In recent years, research has demonstrated that microbes living in and on the mammalian body can affect cancer risk, as well as responses to cancer treatment.