Building A Better Mouse Trap: INTEGRA Biosciences CELLine

The challenge for many laboratories growing hybridoma cell lines is producing adequate amounts of monoclonal antibody (MAb) given the constraints of space, time, and money. Large volumes of antibody typically require an investment in expensive bioreactors, space allocated to a multitude of tissue culture flasks stacked in incubators, or very large mice. "Build a better mouse trap and the world will beat a path to your door," or so the saying goes. With that thought in mind, INTEGRA Biosciences

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

The challenge for many laboratories growing hybridoma cell lines is producing adequate amounts of monoclonal antibody (MAb) given the constraints of space, time, and money. Large volumes of antibody typically require an investment in expensive bioreactors, space allocated to a multitude of tissue culture flasks stacked in incubators, or very large mice.

"Build a better mouse trap and the world will beat a path to your door," or so the saying goes. With that thought in mind, INTEGRA Biosciences (Ijamsville, Md.) has expanded its family of cell cultivation devices and systems with the introduction of its CELLine chambers. Based on membrane technology, the INTEGRA CELLine devices offer a novel approach to cell growth and antibody production.

INTEGRA CELLine 1000 Each of the three different sized devices consists of an upper compartment for cell media and a chamber for cells surrounded by a membrane on each side. The topmost membrane of ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

cytiva logo
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo
Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

cytiva logo

Products

sartorius-logo

Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

parse_logo

Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

shiftbioscience

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

brandtechscientific-logo

BRANDTECH Scientific Launches New Website for VACUU·LAN® Lab Vacuum Systems