Simple dinucleotide repeats are commonly found throughout the human genome, but their functional significance has been unclear. In an Advanced Online Publication in Nature Structural Biology, Jingyi Hui and colleagues describe an unusual role for a CA-repeat in regulating mRNA splicing (Nature Structural Biology, doi:10.1038/nsb875, 25 November 2002).The human endothelial nitric oxide synthase (eNOS) gene contains a polymorphic CA repeat, (CA)14-44, in intron 13 that has been linked to a risk fo
Simple dinucleotide repeats are commonly found throughout the human genome, but their functional significance has been unclear. In an Advanced Online Publication in
The human endothelial nitric oxide synthase (
These results suggest that CA repeats and hnRNP L may regulate the splicing of other genes containing intronic polymorphic repeats.
The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.
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In this half-day virtual summit, a series of presentations will explore the scientific, regulatory, and operational factors impacting the use of in vitro NAMs in drug discovery.
In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.
In this webinar, Magdalena Pacewicz will highlight how to use AUC to characterize AAVs as part of ensuring regulatory compliance.
In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.
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System strengthens Taiwan’s capabilities in protein drug discovery research
The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.
