Cancer gene map online

Global analysis of microarray data provides a hypothesis-generating tool for cancer

Written byCharles Choi
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

The first global analysis of human microarray data, appearing in the October Nature Genetics, maps which gene expression patterns are common among, and unique to, different types of tumors.

The cancer map is publicly available, as is the data analysis and visualization engine, GeneXPress, used to create it. "The tool allows researchers to look not just at single genes, but gives a higher order view by looking at modules of multiple genes at the same time," coauthor of the paper, Aviv Regev of Harvard University, told The Scientist. "And it's very easy to use."

"The whole thing is done in an automated fashion and can work on gene sets from other species besides humans and processes that are not cancer," added Daphne Koller from Stanford University, who also worked on the project.

The researchers scanned a cancer compendium of expression profile data from the Stanford Microarray Database and the Whitehead ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Meet the Author

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

The Scientist Placeholder Image

Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

OGT logo

OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel