Cancer Genetics

Edited by: Eugene Russo Photo: Robert Neroni Photo: Michael Price PERFECT FHIT: Kay Huebner and Carlo Croce of the Kimmel Cancer Center discovered a correlation between the deletion of the FHIT gene and the onset of lung cancer. G. Sozzi, M. L. Veronese, M. Negrini, R. Baffa, M.G. Cotticelli, H. Inoue, S. Tornielli, S. Pilotti, L. De Gregorio, U. Pastorino, M. A. Pierotti, M. Ohta, K. Huebner, C. Croce, "The FHIT gene at 3p14.2 is abnormal in lung cancer," Cell, 85:17-26, 1996. (Cited in mor

Written byEugene Russo

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Edited by: Eugene Russo

Photo: Robert Neroni	Photo: Michael Price

*PERFECT FHIT:* Kay Huebner and Carlo Croce of the Kimmel Cancer Center discovered a correlation between the deletion of the FHIT gene and the onset of lung cancer.

G. Sozzi, M. L. Veronese, M. Negrini, R. Baffa, M.G. Cotticelli, H. Inoue, S. Tornielli, S. Pilotti, L. De Gregorio, U. Pastorino, M. A. Pierotti, M. Ohta, K. Huebner, C. Croce, "The FHIT gene at 3p14.2 is abnormal in lung cancer," Cell, 85:17-26, 1996. (Cited in more than 85 publications as of February 1998) Comments by Carlo Croce, Kimmel Cancer Center, Jefferson Medical College, Philadelphia

Mortality rates for lung cancer victims have not improved significantly in the last 20 years. Recently, scientists have looked to the molecular pathogenesis of the disease in an attempt to improve diagnosis and treatment. The most popular subjects of investigation have been the tumor suppressor gene p53, ...

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