Life Sciences

Rendered image of <em>Chlamydia</em>

How Chlamydia Guards Itself Against the Immune System

Book cover of The Phantom God by John C. Wathey

Opinion: Neuroscience Could Help Demystify Religious Experience

Photo of Monir Moniruzzaman

Monir Moniruzzaman Studies the Secrets of Giant Viruses

<em>Chlamydia</em> invades a host cell, forms a membrane-bound vacuole, or inclusion, and then modifies the protein composition of the structure&rsquo;s membrane. If immune cells detect <em>Chlamydia</em> before it forms the inclusion, they trigger T cells to produce interferon-&gamma; (IFN-&gamma;), a powerful cytokine. IFN-&gamma; activates the protein mysterin (also called RFN213), which attaches ubiquitin to the inclusion membrane, signaling the cell to destroy the inclusion&rsquo;s contents by dumping them into a lysosome (left). C. trachomatis produces GarD, a protein that integrates into the inclusion membrane itself and somehow prevents mysterin from attaching ubiquitin, allowing the bacterium to evade immune destruction while continuing to multiply and eventually bursting from the cell (right).

Infographic: How Chlamydia Evades Immune Detection

A collection of images from previous neuroscience articles, including those of an octopus in a chamber, artistic renditions of a brain, brain scans, and an image of neural connections in vitro.

Our Favorite Neuroscience Stories of 2022

A collection of images from prior stories, including illustrations of DNA, chromosomes, and various cells, microscopy images of cancer cells, and a photo of a mouse on a treadmill.

Our Favorite Cancer Stories of 2022

Collage of faces

Remembering Those We Lost in 2022

composite of images from favorite posts

Our Favorite Genetics Stories of 2022

A fishing cat with a fish in its mouth

Genome Spotlight: Fishing cat (Prionailurus viverrinus)

Artist&rsquo;s rendition of two X chromosomes in blue, with a glowing orange line swirling around one.

Male and Female Stem Cells Derived from One Donor in Scientific First

Training the Immune System to Fight Chronic Diseases

Training the Immune System to Fight Chronic Diseases

illustration of T cell attached to protein

“Smarter” CAR T Cells Target Tumors with Precision

Trending

Kirsty Wright is searching for evidence in a missing persons investigation. She is wearing a blue shirt and glasses. Behind her is dense vegetation and police procedural tape.

How a Forensic Biologist Exposed a DNA Lab Scandal That Shook Australia

An illustration of an in vitro fertilized embryo, which researchers recently used to study maternal aneuploidy

Genetic Basis of Aneuploidy, Which Often Causes Pregnancy Loss, Revealed

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

Multimedia

Layered abstract design representing the structure of 3D cell models.

Transitioning to 3D Cell Models for Better Insights

Inventia Life Science
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

Parse Logo

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform