Charles A. Janeway, Jr., an immunologist known for his work on innate immunity and as the principal author of the acclaimed textbook, Immunobiology: The Immune System in Health and Disease, died after a long struggle with B-cell lymphoma in New Haven, Conn. on April 12. He was 60 years old.

During his 34-year career, Janeway tackled many of immunology's big questions, and he formulated many of the concepts that are the basis of the field today. He made major contributions to the understanding of T-lymphocyte biology and is regarded as the father of innate immunity, the body's first line of defense against infection.

"He was known for generating ideas, often controversial, provocative, and ahead of their time, but often proving to be right — a truly intuitive scientist," said Peter Newmark, copublisher of the first four editions of the Immunobiology textbook. Newmark is now editorial director at The Scientist...

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