Clarification

The article "Trying To Unlock The Mysteries Of Free Radicals And Antioxidants" (A. Mack, The Scientist, Sept. 30, 1996, page 13) included an incorrect description of findings by researchers at Eukarion Inc. in Bedford, Mass., and the University of Southern California. The researchers demonstrated (A.J. Bruce et al., Proceedings of the National Academy of Sciences, 93:2312-6, 1996) that EUK-8-a chemical mimic of the active site of Mn SOD, the mitochondrial form of the enzyme superoxide dismutase


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The article "Trying To Unlock The Mysteries Of Free Radicals And Antioxidants" (A. Mack, The Scientist, Sept. 30, 1996, page 13) included an incorrect description of findings by researchers at Eukarion Inc. in Bedford, Mass., and the University of Southern California. The researchers demonstrated (A.J. Bruce et al., Proceedings of the National Academy of Sciences, 93:2312-6, 1996) that EUK-8-a chemical mimic of the active site of Mn SOD, the mitochondrial form of the enzyme superoxide dismutase-protects neuronal tissue against beta-amyloid toxicity.

The article also gave incorrect information on free radical biology funding from the National Institute on Aging (NIA). NIA spent approximately $71 million, or 15 percent of its 1995-96 budget of $480 million, to support research on oxidative damage related to aging.

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