Cytometry Gets Personal

Does the likelihood of buying a flow cytometer for use in the lab rank right up there with the likelihood of winning the lottery? The high cost of flow cytometers and the dedicated personnel required to operate them usually limit their placement to core facilities. But what if someone were to design a cytometer that was easier to use, didn't need frequent internal adjustment and maintenance, was considerably smaller than a conventional flow cytometer, and carried a bargain price tag? Guava Techn

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Flow cytometry requires that a cell sample be focused into a single-file stream of cells that passes through a laser beam. This is usually achieved by hydrodynamic focusing, whereby the cell sample is drawn out into a fine stream by injecting it into a larger stream of fluid--the sheath fluid. The Guava PC eliminates the need for sheath fluid by injecting the cell sample into a patented fluidic and optical system that similarly analyzes the cells. With no sheath fluid, the amount of waste fluid generated is minimal and there is no need for large sheath and waste fluid tanks. This results in a bench-top cytometer measuring only 36 x 30 x 30 cm. The Guava PC utilizes a high-precision syringe pump to inject the sample into the flow cell and thus can provide absolute cell counts without the need for the types of internal standards used in other flow ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Alison Paladichuk

    This person does not yet have a bio.

Published In

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo