Alison Paladichuk
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Articles by Alison Paladichuk

Code Blue
Alison Paladichuk | | 2 min read
Speed and sensitivity are the key features of GelCode® staining kits from Pierce Chemical Co. of Rockford, Ill. Designed to detect proteins in polyacrylamide gels, the kits include straightforward protocols and standardized reagents to speed up acquisition of data and increase reproducibility of results. "The common feature of the GelCode kits is that they are extremely user-friendly," says Linda Alger, a technical assistance manager with Pierce. In addition, the kits employ optimized chemis

Cytometry Gets Personal
Alison Paladichuk | | 2 min read
Does the likelihood of buying a flow cytometer for use in the lab rank right up there with the likelihood of winning the lottery? The high cost of flow cytometers and the dedicated personnel required to operate them usually limit their placement to core facilities. But what if someone were to design a cytometer that was easier to use, didn't need frequent internal adjustment and maintenance, was considerably smaller than a conventional flow cytometer, and carried a bargain price tag? Guava Techn

Count on ProtoCOL
Alison Paladichuk | | 2 min read
SYNBIOSIS' ProtoCol colony and plaque counter Some researchers spend weeks designing the perfect experiment and executing it with military precision, but before celebrating the fabulous results must confront the mundane chore of counting colonies. "Did I stay in school all these years to do this?" many wonder. In light of an ever-increasing pool of available technology, there must be a more efficient way to do this, right? Right. SYNBIOSIS' ProtoCOL automated colony counter puts an end to the ma

On A Roll: Keep those bottles rollin' with this year's newest hybridization ovens
Alison Paladichuk | | 10+ min read
Date: June 21, 1999 Table of Hybridization Ovens If you've been around molecular biology labs long enough, you'll remember the days when you reached the end of a lengthy probe-labeling procedure and all that was left to do was throw your sizzling probe in with your membrane to hybridize. Sounds like you're almost finished, right? Except it was never that easy. Eliminating air bubbles from sealed plastic bags without squeezing out your precious probe and contaminating the bag sealer, the bench,

How the Western Was Won: A Profile of Tools and Kits Available for Western Blotting
Alison Paladichuk | | 10+ min read
Date: March 15, 1999Western Detection Kit Table Are you a pipette-totin,' membrane-slingin' Western blotter? Or are you a shotgun cloner who's venturing out West for the first time? Either way, you might want to join us as we take a trip to the frontier to check out pioneering products available to make your life easier and your blots better. In this profile, LabConsumer looks at the latest tools and kits that are available to enhance Western blotting--from blotting equipment that ensures even

Fishing In A Molecular Sea
Alison Paladichuk | | 10+ min read
Date: January 18, 1999Labeling Kit Companies Labeling Kit Companies: Details In situ spatial localization of mRNA expressed only after ethylene treatment (left) compared to air grown seedlings used as a negative control (right). The RNA probe to the EIA0305 gene was labeled with fluorescein (NEL633) and visualized with NBT (Image courtesy of New England Nuclear) Remember the days when fishing for a sequence in the E. coli genome seemed like an overwhelming task? Somewhere along the way, it see

Stovall Washes Whiter (And Quicker)
Alison Paladichuk | | 3 min read
Stovall Life Sciences Inc. makes the fully automated Washing Machine™ for the repetitive tasks of processing blots, and staining and destaining gels. The Washing Machine from Stovall Life Sciences, Inc. When is a 30-minute job not a 30-minute job? When it includes intervals that are just too long to sit and do nothing and just too short to accomplish other tasks. The intervals get longer and longer, and, the 30-minute job ends up taking three times as long. Such is the case of processi

Cells on the Move
Alison Paladichuk | | 4 min read
With the Cell Sedimentation Manifold from Creative Scientific Methods, Inc., migration assays are convenient and reproducible Studies of cell migration can reveal much in the study of cancer, arteriosclerosis, arthritis, autoimmune diseases, inflammatory conditions, and wound healing. Because of the many roles cell migration plays in pathological processes, any new technology for use in migration assays promises to have a significant impact on biomedical research. Development of the Cell Sedime
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